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Article

Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.

Life science alliance - 1 Aug 2019

Korntner-Vetter Melanie, Lefèvre Stéphane, Hu Xiao-Wen, George Roger, Singleton Martin R

Abstract excerpt

Centromeric chromatin in fission yeast is distinguished by the presence of nucleosomes containing the histone H3 variant Cnp1CENP-A Cell cycle-specific deposition of Cnp1 requires the Mis16-Mis18-Mis19 complex, which is thought to direct recruitment of Scm3-chaperoned Cnp1/histone H4 dimers to DNA. Here, we present the structure of the essential Mis18 partner protein Mis19 and describe its interaction with Mis16,...

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Identifiers

PMID: 31371524
DOI: 10.26508/lsa.201900408
PMCID: PMC6677171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.PMID 31371524Read ↗

Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.Semantic proximity Read ↗

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Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore.Semantic proximity Read ↗

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