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Article

Fission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatin.

Molecular cell - 13 Feb 2009

Pidoux Alison L, Choi Eun Shik, Abbott Johanna K R, Liu Xingkun, Kagansky Alexander, Castillo Araceli G, Hamilton Georgina L, Richardson William, Rappsilber Juri, He Xiangwei, Allshire Robin C

Abstract excerpt

The mechanisms ensuring specific incorporation of CENP-A at centromeres are poorly understood. Mis16 and Mis18 are required for CENP-A localization at centromeres and form a complex that is conserved from fission yeast to human. Fission yeast sim1 mutants that alleviate kinetochore domain silenci...

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Identifiers

PMID: 19217404
DOI: 10.1016/j.molcel.2009.01.019
PMCID: PMC2697330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19217404-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Fission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatin.PMID 19217404Read ↗

A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.Semantic proximity Read ↗

Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.Semantic proximity Read ↗

Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.Semantic proximity Read ↗

Scm3 interacts with the N-terminal tail of Cse4 to regulate kinetochore assembly in budding yeastSemantic proximity Read ↗

Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathwaySemantic proximity Read ↗

Scm3, an essential Saccharomyces cerevisiae centromere protein required for G2/M progression and Cse4 localization.Semantic proximity Read ↗

Scm3 is a centromeric nucleosome assembly factor.Semantic proximity Read ↗

Subunit interactions and arrangements in the fission yeast Mis16-Mis18-Mis19 complex.Semantic proximity Read ↗

A DNA polymerase alpha accessory protein, Mcl1, is required for propagation of centromere structures in fission yeast.Semantic proximity Read ↗

CENP-C functions as a scaffold for effectors with essential kinetochore functions in mitosis and meiosis.Semantic proximity Read ↗

De novo kinetochore assembly requires the centromeric histone H3 variant.Semantic proximity Read ↗

Requirement of Mis6 centromere connector for localizing a CENP-A-like protein in fission yeast.Semantic proximity Read ↗

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