Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast.

Scientific reports - 15 Sept 2015

Lim Kim Kiat, Ong Terenze Yao Rui, Tan Yue Rong, Yang Eugene Guorong, Ren Bingbing, Seah Kwi Shan, Yang Zhe, Tan Tsu Soo, Dymock Brian W, Chen Ee Sin

Abstract excerpt

Eukaryotic genomes are packed into discrete units, referred to as nucleosomes, by organizing around scaffolding histone proteins. The interplay between these histones and the DNA can dynamically regulate the function of the chromosomal domain. Here, we interrogated the function of a pair of juxtaposing serine residues (S86 and S87) that reside within the histone fold of histone H3. We show that fission yeast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centromere
Share to Chromosome Segregation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA Transcription Factors

Share to Gene Expression Regulation, Fungal

Share to Histones

Share to Protein Biosynthesis

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 26369364
DOI: 10.1038/srep14064
PMCID: PMC4570208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast.PMID 26369364Read ↗

A NASP (N1/N2)-related protein, Sim3, binds CENP-A and is required for its deposition at fission yeast centromeres.Semantic proximity Read ↗

A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.Semantic proximity Read ↗

Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.Semantic proximity Read ↗

Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast.Semantic proximity Read ↗

mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.Semantic proximity Read ↗

Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast.Semantic proximity Read ↗

Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function.Semantic proximity Read ↗

Fission yeast Scm3: A CENP-A receptor required for integrity of subkinetochore chromatin.Semantic proximity Read ↗

Sim4: a novel fission yeast kinetochore protein required for centromeric silencing and chromosome segregation.Semantic proximity Read ↗

Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3.Semantic proximity Read ↗

Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.Semantic proximity Read ↗

Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.