Article
The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres.
Nucleic acids research - 1 Jan 2005
Walfridsson Julian, Bjerling Pernilla, Thalen Maria, Yoo Eung-Jae, Park Sang Dai, Ekwall Karl
Abstract excerpt
Centromeres of fission yeast are arranged with a central core DNA sequence flanked by repeated sequences. The centromere-associated histone H3 variant Cnp1 (SpCENP-A) binds exclusively to central core DNA, while the heterochromatin proteins and cohesins bind the surrounding outer repeats. CHD (chromo-helicase/ATPase DNA binding) chromatin remodeling factors were recently shown to affect chromatin assembly in...
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