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Article

Multilayer View of Pathogenic SNVs in Human Interactome through In Silico Edgetic Profiling.

Journal of molecular biology - 14 Sept 2018

Cui Hongzhu, Zhao Nan, Korkin Dmitry

Abstract excerpt

Non-synonymous mutations linked to the complex diseases often have a global impact on a biological system, affecting large biomolecular networks and pathways. However, the magnitude of the mutation-driven effects on the macromolecular network is yet to be fully explored. In this work, we present a systematic multi-level characterization of human mutations associated with genetic disorders by determining their...

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Identifiers

PMID: 30017919
DOI: 10.1016/j.jmb.2018.07.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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