Article

Multilayer view of pathogenic SNVs in human interactome through <i>in-silico</i> edgetic profiling

2018-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Non-synonymous mutations linked to the complex diseases often have a global impact on a biological system, affecting large biomolecular networks and pathways. However, the magnitude of the mutation-driven effects on the macromolecular network is yet to be fully explored. In this work, we present an systematic multi-level characterization of human mutations associated with genetic disorders by de...

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Literature Corpus work: ae5c71a5-2377-5b5f-aeb5-6f1f2364aa70
DOI: 10.1101/299891

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