Article
Enriching Human Interactome with Functional Mutations to Detect High-Impact Network Modules Underlying Complex Diseases.
Genes - 15 Nov 2019
Cui Hongzhu, Srinivasan Suhas, Korkin Dmitry
Abstract excerpt
Rapid progress in high-throughput -omics technologies moves us one step closer to the datacalypse in life sciences. In spite of the already generated volumes of data, our knowledge of the molecular mechanisms underlying complex genetic diseases remains limited. Increasing evidence shows that biological networks are essential, albeit not sufficient, for the better understanding of these mechanisms. The...
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