The Extent of Edgetic Perturbations in the Human Interactome Caused by Population-Specific Mutations.

Abstract excerpt

Until recently, efforts in population genetics have been focused primarily on people of European ancestry. To attenuate this bias, global population studies, such as the 1000 Genomes Project, have revealed differences in genetic variation across ethnic groups. How many of these differences can be attributed to population-specific traits? To answer this question, the mutation data must be linked with functional...

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