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Article

Saccade latency delays in young apolipoprotein E (APOE) epsilon 4 carriers.

Behavioural brain research - 1 Nov 2018

Niechwiej-Szwedo Ewa, Tapper Anthony, Gonzalez David, Bradley Ryan M, Duncan Robin

Abstract excerpt

The apolipoprotein E (APOE) epsilon 4 isoform has been associated with a significantly greater risk of developing late onset Alzheimer's disease (AD). However, the negative effects of APOE-ε4 allele on cognitive function vary across the lifespan: reduced memory and executive function have been found in older individuals but, paradoxically, young APOE-ε4 carriers perform better on cognitive tests and show higher...

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Source

Identifiers

PMID: 30003976
DOI: 10.1016/j.bbr.2018.07.002

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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