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Article

The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline.

Neurobiology of aging - 1 Dec 2016

Lancaster Claire, Tabet Naji, Rusted Jennifer

Abstract excerpt

Possession of an Apolipoprotein E (APOE) e4 allele is an established risk factor for Alzheimer's disease, whereas the less commonly studied e2 variant is premised to offer some protection. This research explores the purported deleterious-protective dichotomy of APOE variants on attentional control in mid-adulthood. Sixty-six volunteers, aged 45-55 years, completed 3 tasks that provided complementary measures of...

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Source

Identifiers

PMID: 27661410
DOI: 10.1016/j.neurobiolaging.2016.08.015

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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