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Article

Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers.

Sleep - 11 Jul 2024

André Claire, Martineau-Dussault Marie-Ève, Baril Andrée-Ann, Marchi Nicola Andrea, Daneault Véronique, Lorrain Dominique, Hudon Carol, Bastien Célyne H, Petit Dominique, Thompson Cynthia, Poirier Judes, Montplaisir Jacques, Gosselin Nadia, Carrier Julie

Abstract excerpt

STUDY OBJECTIVES: Apolipoprotein E ɛ4 (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD). In addition, APOE4 carriers may exhibit sleep disturbances, but conflicting results have been reported, such that there is no clear consensus regarding which aspects of sleep are impacted. Our objective was to compare objective sleep architecture between APOE4 carriers and non-carriers, and to...

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Identifiers

PMID: 38634644
DOI: 10.1093/sleep/zsae094
PMCID: PMC11236949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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