Slower speed-of-processing of cognitive tasks is associated with presence of the apolipoprotein epsilon4 allele.

doi:10.1016/j.jpsychires.2006.12.001

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Article

Slower speed-of-processing of cognitive tasks is associated with presence of the apolipoprotein epsilon4 allele.

Journal of psychiatric research - 1 Feb 2008

O'Hara Ruth, Sommer Barbara, Way Nate, Kraemer Helena C, Taylor Joy, Murphy Greer

Abstract excerpt

Detection of preclinical cognitive deficits is important for identifying those at greatest risk for such disorders as Alzheimer's disease. However, available neuropsychological measures may not be sufficiently sensitive to preclinical cognitive impairment, particularly in high functioning or younger older adults. This study utilizes a battery of computerized cognitive tests (Cognometer) designed to provide a more...

Topics

Aged
Aging
Alleles
Alzheimer Disease
Apolipoprotein E4
Cognition Disorders
Female
Genotype
Humans
Male
Mass Screening
Memory Disorders
Memory, Short-Term
Neuropsychological Tests
Prevalence

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Open in PubMed

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PMID: 17250852
DOI: 10.1016/j.jpsychires.2006.12.001

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