Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults.

doi:10.1002/1096-8628(20001204)96:6<707::aid-ajmg1>3.0.co;2-v

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Article

Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults.

American journal of medical genetics - 4 Dec 2000

Flory J D, Manuck S B, Ferrell R E, Ryan C M, Muldoon M F

Abstract excerpt

The apolipoprotein E genotype (APOE) is an established risk factor for Alzheimer disease, with the age-at-onset occurring earlier in individuals having at least one APOE epsilon 4 allele, relative to the APOE epsilon 3 or APOE epsilon 2 isoforms. Moreover, nondemented older adults with the APOE e...

Topics

Adult
Alleles
Apolipoproteins E
Cohort Studies
DNA
Female
Gene Frequency
Genotype
Humans
Learning
Male
Memory
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Polymorphism, Genetic
Sampling Studies

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