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Article

Bulky DNA adduct levels in normal-appearing colon mucosa, and the prevalence of colorectal adenomas.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Dec 2018

Ho Vikki, Peacock Sarah, Massey Thomas E, Godschalk Roger W, van Schooten Frederik J, Ashbury Janet E, Vanner Stephen J, King Will D

Abstract excerpt

PURPOSE: Examine the association between bulky DNA adduct levels in colon mucosa and colorectal adenoma prevalence, and explore the correlation between adduct levels in leukocytes and colon tissue. METHODS: Bulky DNA adduct levels were measured using 32P-postlabelling in biopsies of normal-appearing colon tissue and blood donated by 202 patients. Multivariable logistic regression was used to examine associations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29871536
DOI: 10.1080/1354750X.2018.1485055

Genes

XPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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