Article
Efficiency of Base Excision Repair of Oxidative DNA Damage and Its Impact on the Risk of Colorectal Cancer in the Polish Population.
Oxidative medicine and cellular longevity - 1 Jan 2016
Kabzinski J, Mucha B, Cuchra M, Markiewicz L, Przybylowska K, Dziki A, Dziki L, Majsterek I
Abstract excerpt
DNA oxidative lesions are widely considered as a potential risk factor for colorectal cancer development. The aim of this work was to determine the role of the efficiency of base excision repair, both in lymphocytes and in epithelial tissue, in patients with CRC and healthy subjects. SNPs were identified within genes responsible for steps following glycosylase action in BER, and patients and healthy subjects were...
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