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Article

Telomere length and genetics are independent colorectal tumour risk factors in an evaluation of biomarkers in normal bowel.

British journal of cancer - 6 Mar 2018

Fernandez-Rozadilla Ceres, Kartsonaki Christiana, Woolley Connor, McClellan Michael, Whittington Deb, Horgan Gareth, Leedham Simon, Kriaucionis Skirmantas, East James, Tomlinson Ian

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) screening might be improved by using a measure of prior risk to modulate screening intensity or the faecal immunochemical test threshold. Intermediate molecular biomarkers could aid risk prediction by capturing both known and unknown risk factors. METHODS: We sampled normal bowel mucosa from the proximal colon, distal colon and rectum of 317 individuals undergoing colonoscopy....

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Source

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Identifiers

PMID: 29438375
DOI: 10.1038/bjc.2017.486
PMCID: PMC5846076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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