Article

Colorectal cancer risk in bowel adenomas based on lifestyle exposures, tissue preconditioning and DNA methylation

2021-08-27

Abstract excerpt

<h4>Background</h4> Colorectal cancer (CRC) is associated with patient demographics, lifestyle exposures and molecular alterations. However, it is not possible to determine which adenomas will progress to CRC, as ethically it is unacceptable to leave and follow adenomas. We hypothesised that certain lifestyle exposures at high levels could precondition exposed bowel tissue by changing and aging it, increasing the...

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Literature Corpus work: b86c8bc0-7190-54e3-ab70-0dd9726c4dcf
DOI: 10.1101/2021.08.26.457788

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