Article
The genetic basis for DNA methylation variation across tissues and development
2025-09-16
Abstract excerpt
The mechanisms by which genetic variation shapes the epigenome across cell types and developmental stages have remained elusive. Here, we define a unifying developmental framework for DNA methylation programming, grounded in genome-wide methylation and genetic variation data from both mouse and human. In mice, we identify thousands of differentially methylated regions (DMRs) linked to sequence polymorphisms that d...
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Identifiers and source
- Literature Corpus work
- 828cf517-fef2-5d35-9875-7b1ee6f1c454
- DOI
- 10.1101/2025.09.15.675351