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Gene mutation and micronucleus assays in gpt delta mice treated with 2,2',4,4'-tetrabromodiphenyl ether.

Mutagenesis - 13 Apr 2018

You Xinyue, Ando Tomoko, Xi Jing, Cao Yiyi, Liu Weiying, Zhang Xinyu, Honma Masamitsu, Masumura Kenichi, Luan Yang

Abstract excerpt

Flame retardant polybrominated diphenyl ethers (PBDEs) are a class of persistent organic pollutants (POPs). 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) is a representative PBDE congener with widespread distribution and relatively high toxicity potential. Although it has been reported that BDE-47 can cause DNA damage in various in vitro systems, few studies have provided in vivo genotoxicity information. The aim...

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PMID: 29462428
DOI: 10.1093/mutage/gey002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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