Article
Gene mutation and micronucleus assays in gpt delta mice treated with 2,2',4,4'-tetrabromodiphenyl ether.
Mutagenesis - 13 Apr 2018
You Xinyue, Ando Tomoko, Xi Jing, Cao Yiyi, Liu Weiying, Zhang Xinyu, Honma Masamitsu, Masumura Kenichi, Luan Yang
Abstract excerpt
Flame retardant polybrominated diphenyl ethers (PBDEs) are a class of persistent organic pollutants (POPs). 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) is a representative PBDE congener with widespread distribution and relatively high toxicity potential. Although it has been reported that BDE-47...
Topics
- Animals
- DNA Damage
- Environmental Pollutants
- Escherichia coli Proteins
- Halogenated Diphenyl Ethers
- Liver
- Membrane Proteins
- Mice
- Mice, Transgenic
- Micronucleus Tests
- Mutagenicity Tests
- Mutagens