Article
In vivo reporter gene mutation and micronucleus assays in gpt delta mice treated with a flame retardant decabromodiphenyl ether.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Apr 2017
Takasu Shinji, Ishii Yuji, Yokoo Yuh, Tsuchiya Takuma, Kijima Aki, Kodama Yukio, Ogawa Kumiko, Umemura Takashi
Abstract excerpt
Polybrominated diphenyl ethers (PBDEs), a class of brominated flame retardants, have been widely used as additive flame retardants. Recently, the use of brominated flame retardants has been restricted or prohibited under various legislative acts because of the persistence, bioaccumulation potenti...
Topics
- Animals
- Biological Assay
- DNA Damage
- Disease Models, Animal
- Flame Retardants
- Genes, Reporter
- Halogenated Diphenyl Ethers
- Liver
- Male
- Mice
- Micronucleus Tests
- Mutation