Article
Fsh-Pc-Sce complex mediates active transcription of Cubitus interruptus (Ci).
Journal of molecular cell biology - 1 Oct 2018
Lv Xiangdong, Chen Hao, Zhang Shuo, Zhang Zhao, Pan Chenyu, Xia Yuanxin, Fan Jialin, Wu Wenqing, Lu Yi, Zhang Lei, Wu Hailong, Zhao Yun
Abstract excerpt
The Hedgehog (Hh) signaling pathway plays important roles in both embryonic development and adult tissue homeostasis. Such biological functions are mediated by the transcription factor Cubitus interruptus (Ci). Yet the transcriptional regulation of the effector Ci itself is poorly investigated. Through an RNAi-based genetic screen, we identified that female sterile (1) homeotic (Fsh), a transcription...
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