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Article

The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo.

Molecular cell - 24 Jun 2011

Chopra Vivek S, Hendrix David A, Core Leighton J, Tsui Chiahao, Lis John T, Levine Michael

Abstract excerpt

Many developmental control genes contain paused RNA polymerase II (Pol II) and are thereby "poised" for rapid and synchronous activation in the early Drosophila embryo. Evidence is presented that Polycomb group (PcG) repressors can influence paused Pol II. ChIP-Seq and GRO-Seq assays were used to determine the genome-wide distributions of Pol II, H3K27me3, and H3K4me3 in extra sex combs (esc) mutant embryos. ESC...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 21700228
DOI: 10.1016/j.molcel.2011.05.009
PMCID: PMC3130001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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