Article
The extra sex combs product contains WD40 repeats and its time of action implies a role distinct from other Polycomb group products.
Mechanisms of development - 1 Oct 1995
Simon J, Bornemann D, Lunde K, Schwartz C
Abstract excerpt
The extra sex combs (esc) gene product is a transcriptional repressor of homeotic genes. Although it is classified in the Polycomb group (PcG) on the basis of phenotypic criteria, it is distinct from most other PcG repressors in its time of action during development. We describe the temporal prof...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Consensus Sequence
- Drosophila
- Gene Expression Regulation, Developmental
- Genes, Homeobox
- Genes, Insect
- Molecular Sequence Data
- Phenotype
- Protein Structure, Tertiary
- Repressor Proteins
- Time Factors