Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The extra sex combs product contains WD40 repeats and its time of action implies a role distinct from other Polycomb group products.

Mechanisms of development - 1 Oct 1995

Simon J, Bornemann D, Lunde K, Schwartz C

Abstract excerpt

The extra sex combs (esc) gene product is a transcriptional repressor of homeotic genes. Although it is classified in the Polycomb group (PcG) on the basis of phenotypic criteria, it is distinct from most other PcG repressors in its time of action during development. We describe the temporal profile of esc mRNA expression during embryogenesis and the stage-specific rescue of esc mutants with a heat...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Drosophila

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Genes, Insect

Share to Molecular Sequence Data

Share to Phenotype

Share to Time Factors

Source

Identifiers

PMID: 8562422
DOI: 10.1016/0925-4773(95)00434-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The extra sex combs product contains WD40 repeats and its time of action implies a role distinct from other Polycomb group products.PMID 8562422Read ↗

The Drosophila extra sex combs protein contains WD motifs essential for its function as a repressor of homeotic genes.Semantic proximity Read ↗

A Drosophila ESC-E(Z) protein complex is distinct from other polycomb group complexes and contains covalently modified ESC.Semantic proximity Read ↗

Polycomb group proteins ESC and E(Z) are present in multiple distinct complexes that undergo dynamic changes during development.Semantic proximity Read ↗

Persistent ectopic expression of Drosophila homeotic genes resulting from maternal deficiency of the extra sex combs gene product.Semantic proximity Read ↗

The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes.Semantic proximity Read ↗

Screen for enhancers of Polycomb and Polycomblike in Drosophila melanogaster.Semantic proximity Read ↗

Interactions of polyhomeotic with Polycomb group genes of Drosophila melanogaster.Semantic proximity Read ↗

Additional Sex Combs-like Family Associated with Epigenetic Regulation.Semantic proximity Read ↗

Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function.Semantic proximity Read ↗

Additional Sex Combs-Like Family Associated with Epigenetic RegulationSemantic proximity Read ↗

The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins.Semantic proximity Read ↗

Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.