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Article

Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function.

Molecular and cellular biology - 1 Aug 2005

King Ian F G, Emmons Richard B, Francis Nicole J, Wild Brigitte, Müller Jürg, Kingston Robert E, Wu Chao-Ting

Abstract excerpt

Polycomb group (PcG) genes propagate patterns of transcriptional repression throughout development. The products of several such genes are part of Polycomb repressive complex 1 (PRC1), which inhibits chromatin remodeling and transcription in vitro. Genetic and biochemical studies suggest the product of the Posterior sex combs (Psc) gene plays a central role in both PcG-mediated gene repression in vivo and PRC1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16024794
DOI: 10.1128/MCB.25.15.6578-6591.2005
PMCID: PMC1190323

Genes

PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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