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Article

Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.

Genetics - 1 Feb 1995

Gindhart J G, Kaufman T C

Abstract excerpt

The Drosophila homeotic gene Sex combs reduced (Scr) is necessary for the establishment and maintenance of the morphological identity of the labial and prothoracic segments. In the early embryo, its expression pattern is established through the activity of several gap and segmentation gene products, as well as other transcription factors. Once established, the Polycomb group (Pc-G) and trithorax group (trx-G)...

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Identifiers

PMID: 7713433
DOI: 10.1093/genetics/139.2.797
PMCID: PMC1206382

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Identification of Polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced.PMID 7713433Read ↗

The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development.Semantic proximity Read ↗

A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster.Semantic proximity Read ↗

Transvection and silencing of the Scr homeotic gene of Drosophila melanogaster.Semantic proximity Read ↗

Analysis of the sequence and phenotype of Drosophila Sex combs reduced alleles reveals potential functions of conserved protein motifs of the Sex combs reduced protein.Semantic proximity Read ↗

Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster.Semantic proximity Read ↗

A complex array of DNA-binding proteins required for pairing-sensitive silencing by a polycomb group response element from the Drosophila engrailed gene.Semantic proximity Read ↗

The extra sex combs product contains WD40 repeats and its time of action implies a role distinct from other Polycomb group products.Semantic proximity Read ↗

The Additional sex combs gene of Drosophila is required for activation and repression of homeotic loci, and interacts specifically with Polycomb and super sex combs.Semantic proximity Read ↗

A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats.Semantic proximity Read ↗

Persistent ectopic expression of Drosophila homeotic genes resulting from maternal deficiency of the extra sex combs gene product.Semantic proximity Read ↗

The Drosophila Polycomb group gene Sex combs extra encodes the ortholog of mammalian Ring1 proteins.Semantic proximity Read ↗

The Drosophila extra sex combs protein contains WD motifs essential for its function as a repressor of homeotic genes.Semantic proximity Read ↗

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