The Drosophila extra sex combs protein contains WD motifs essential for its function as a repressor of homeotic genes.

doi:10.1016/0925-4773(95)00392-e

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Article

The Drosophila extra sex combs protein contains WD motifs essential for its function as a repressor of homeotic genes.

Mechanisms of development - 1 Jul 1995

Sathe S S, Harte P J

Abstract excerpt

Extra sex combs is a member of the Polycomb Group genes, whose products are required for stable long term transcriptional repression of the homeotic genes of the Bithorax and Antennapedia complexes. The Pc-G proteins are required to maintain the spatially restricted domains of homeotic gene expression established by the transiently expressed repressors, e.g., hunchback, but are not required for the functioning of...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
Genes, Homeobox
Histone-Lysine N-Methyltransferase
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polycomb Repressive Complex 1

Polycomb Repressive Complex 2

Proteins

Repetitive Sequences, Nucleic Acid

Sequence Analysis

Source

Open in PubMed

Identifiers

PMID: 7577677
DOI: 10.1016/0925-4773(95)00392-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7577677-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The Drosophila extra sex combs protein contains WD motifs essential for its function as a repressor of homeotic genes.PMID 7577677Read ↗

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