Article
A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis.
G3 (Bethesda, Md.) - 9 Aug 2016
Ables Elizabeth T, Hwang Grace H, Finger Danielle S, Hinnant Taylor D, Drummond-Barbosa Daniela
Abstract excerpt
Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While the transcriptional targets of ecdysone signaling during development have been studied extensively, targets in the ovary remain largely unknown. Early studies of salivary gland polytene chromosomes led to a model in which ecdysone...
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