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Article

Accurate determination of the CYP2D6 (1/4)xN genotype by quantitative PCR.

Drug metabolism and personalized therapy - 28 Mar 2018

Pondman Kirsten M, van Schaik Ron H N, van der Weide Jan

Abstract excerpt

BACKGROUND: CYP2D6 is responsible for the metabolism of approximately 25% of all drugs. The expression of cytochrome P450 2D6 (CYP2D6) is influenced by a combination of factors including polymorphisms in the CYP2D6 gene. Analysis of the CYP2D6 genotype is used to personalize the medication to a patient's metabolism. Although many genotypes can be determined using standard genotype analysis, in some cases, an...

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PMID: 29420304
DOI: 10.1515/dmpt-2017-0007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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