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Article

Unique Genotyping Protocol of CYP2D6 Allele Frequency Using Real Time Quantitative PCR from Japanese Healthy Women.

Biological & pharmaceutical bulletin - 1 Jan 2020

Kisoi Madoka, Imai Miho, Yamamura Miwako, Sakaguchi Yui, Murata Shigenori, Ichikawa Atsushi, Kinoshita Kenji

Abstract excerpt

CYP2D6 is an important drug-metabolizing enzyme involved in the metabolism of 20-25% of commonly prescribed drugs. Genetic polymorphism of CYP has clinically significant modifications in patients' drug-metabolizing capacities. Since gene copy number variation (CNV) and single nucleotide polymorphism (SNP) frequently occur in the CYP2D6 gene, which the activity of CYP2D6 particularly depend on the genetic factors....

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Identifiers

PMID: 32378566
DOI: 10.1248/bpb.b19-00512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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