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Article

CYP2D6, SULT1A1 and UGT2B17 copy number variation: quantitative detection by multiplex PCR.

Pharmacogenomics - 1 Jan 2012

Gaedigk Andrea, Twist Greyson P, Leeder J Steven

Abstract excerpt

AIM: Among the genes of drug-metabolizing enzymes, CYP2D6 is notoriously difficult to characterize owing to the complexity of gene deletions, duplications, multiplications and the presence of hybrid genes composed of CYP2D6 and CYP2D7. For SULT1A1 up to five gene copies have been reported, while UGT2B17 is known for gene deletions only. Different platforms exist for copy number variation (CNV) detection; however,...

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Identifiers

PMID: 22111604
DOI: 10.2217/pgs.11.135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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