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Article

Complexities of CYP2D6 gene analysis and interpretation.

International review of psychiatry (Abingdon, England) - 1 Oct 2013

Gaedigk Andrea

Abstract excerpt

Cytochrome P450 2D6 (CYP2D6) plays an important role in the metabolism and bioactivation of about 25% of clinically used drugs including many antidepressants, antipsychotics and opioids. CYP2D6 activity is highly variably ranging from no activity in so-called poor metabolizers to ultrarapid metabolism at the other end of the extreme of the activity distribution. A large portion of this variability can be...

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Source

Identifiers

PMID: 24151800
DOI: 10.3109/09540261.2013.825581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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