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Article

Rapid detection of common cytochrome P450 2D6 alleles in Caucasians.

Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2006

Roberts Rebecca L, Kennedy Martin A

Abstract excerpt

CYP2D6 is a highly polymorphic enzyme that mediates the metabolism of around 20% of all currently prescribed drugs. Genetic variability within CYP2D6 results in poor (PM), intermediate (IM), extensive (EM) and ultra-rapid metabolisers (UM) of CYP2D6 substrates. Here we describe an assay which is able to detect the major PM (CYP2D6*3, *4, *5, *6), IM (CYP2D6*9, *10, *41) and UM (CYP2D6*nxn) alleles found in...

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Identifiers

PMID: 16364273
DOI: 10.1016/j.cca.2005.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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