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Article

In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate.

The Journal of experimental medicine - 2 Jan 2018

Eich Christina, Arlt Jochen, Vink Chris S, Solaimani Kartalaei Parham, Kaimakis Polynikis, Mariani Samanta A, van der Linden Reinier, van Cappellen Wiggert A, Dzierzak Elaine

Abstract excerpt

Cell fate is established through coordinated gene expression programs in individual cells. Regulatory networks that include the Gata2 transcription factor play central roles in hematopoietic fate establishment. Although Gata2 is essential to the embryonic development and function of hematopoietic stem cells that form the adult hierarchy, little is known about the in vivo expression dynamics of Gata2 in single...

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Identifiers

PMID: 29217535
DOI: 10.1084/jem.20170807
PMCID: PMC5748852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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