Article

Single-cell tracing of the first hematopoietic stem cell generation in human embryos

2019-08-29

Abstract excerpt

Tracing the emergence of the first hematopoietic stem cells (HSCs) in human embryos, particularly the scarce and transient precursors thereof, is so far challenging, largely due to technical limitations and material rarity. Here, using single-cell RNA sequencing, we constructed the first genome-scale gene expression landscape covering the entire course of endothelial-to-HSC transition during human embryogenesis. T...

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Literature Corpus work: 06035fb7-97ea-5dfe-8680-2abbd5a2ad56
DOI: 10.1101/750158

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