Article

A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

2023-04-06

Abstract excerpt

The outflow tract (OFT) of the heart carries blood away from the heart into the great arteries. During embryogenesis, the OFT divides to form the aorta and pulmonary trunk, creating the double circulation present in mammals. Defects in this area account for one-third of all congenital heart defect cases. Here, we present comprehensive transcriptomic data on the developing OFT at two distinct timepoints (embryonic...

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Literature Corpus work: b9718d9f-2e60-537c-bb34-98aad3a7445e
DOI: 10.1101/2023.04.05.535627

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