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Article

Context-dependent GATA Factor Function

9 Mar 2007

Abstract excerpt

GATA factors are fundamental components of developmentally important transcriptional networks. By contrast to common mechanisms in which transacting factors function directly at promoters, the hematopoietic GATA factors GATA-1 and GATA-2 often assemble dispersed complexes over broad chromosomal regions. For example, GATA-1 and GATA-2 occupy five conserved regions over approximately 100 kb of the Gata2 locus in...

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PMID: 17347142
DOI: 10.1074/jbc.m700792200

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