Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.

Molecular and cellular biology - 1 Aug 2005

Kobayashi-Osaki Maki, Ohneda Osamu, Suzuki Norio, Minegishi Naoko, Yokomizo Tomomasa, Takahashi Satoru, Lim Kim-Chew, Engel James Douglas, Yamamoto Masayuki

Abstract excerpt

Transcription factor GATA-2 is essential for definitive hematopoiesis, which developmentally emerges from the para-aortic splanchnopleura (P-Sp). The expression of a green fluorescent protein (GFP) reporter placed under the control of a 3.1-kbp Gata2 gene regulatory domain 5' to the distal first exon (IS) mirrored that of the endogenous Gata2 gene within the P-Sp and yolk sac (YS) blood islands of embryonic day...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Transgenes
Share to Amino Acid Motifs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD34

Share to Cell Lineage

Share to GATA2 Transcription Factor

Share to Hematopoietic Stem Cells

Share to Proto-Oncogene Proteins c-kit

Share to Stromal Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 16055713
DOI: 10.1128/MCB.25.16.7005-7020.2005
PMCID: PMC1190224

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.PMID 16055713Read ↗

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.Semantic proximity Read ↗

A<i>Gata2</i>intronic enhancer confers its pan-endothelia-specific regulationSemantic proximity Read ↗

In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate.Semantic proximity Read ↗

<i>Gata2</i> -regulated <i>Gfi1b</i> expression controls endothelial programming during endothelial-to-hematopoietic transitionSemantic proximity Read ↗

Context-dependent GATA Factor FunctionSemantic proximity Read ↗

Gata2 is required for HSC generation and survival.Semantic proximity Read ↗

Generation and Analysis of GATA2w/eGFP Human ESCs Reveal ITGB3/CD61 as a Reliable Marker for Defining Hemogenic Endothelial Cells during Hematopoiesis.Semantic proximity Read ↗

Induction of a hemogenic program in mouse fibroblasts.Semantic proximity Read ↗

Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.Semantic proximity Read ↗

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.Semantic proximity Read ↗

Roles of Hematopoietic Transcription Factors GATA-1 and GATA-2 in the Development of Red Blood Cell LineageSemantic proximity Read ↗

A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.