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Article

IgE sensitization in relation to preschool eczema and filaggrin mutation.

The Journal of allergy and clinical immunology - 1 Dec 2017

Johansson Emma Kristin, Bergström Anna, Kull Inger, Lind Tomas, Söderhäll Cilla, van Hage Marianne, Wickman Magnus, Ballardini Natalia, Wahlgren Carl-Fredrik

Abstract excerpt

BACKGROUND: Eczema (atopic dermatitis) is associated with an increased risk of having IgE antibodies. IgE sensitization can occur through an impaired skin barrier. Filaggrin gene (FLG) mutation is associated with eczema and possibly also with IgE sensitization. OBJECTIVE: We sought to explore the longitudinal relation between preschool eczema (PSE), FLG mutation, or both and IgE sensitization in childhood....

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Source

Identifiers

PMID: 28456621
DOI: 10.1016/j.jaci.2017.04.008

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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