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Article

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma.

The Journal of allergy and clinical immunology - 1 Apr 2009

Marenholz Ingo, Kerscher Tamara, Bauerfeind Anja, Esparza-Gordillo Jorge, Nickel Renate, Keil Thomas, Lau Susanne, Rohde Klaus, Wahn Ulrich, Lee Young-Ae

Abstract excerpt

BACKGROUND: Asthma prediction in early infancy is essential for the development of new preventive strategies. Loss-of-function mutations in the filaggrin gene (FLG) were identified as risk factors for eczema and associated asthma. OBJECTIVE: We evaluated the utility of the FLG mutations for the prediction of asthma. METHODS: Eight hundred seventy-one individuals of the prospective German Multicenter Allergy Study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19348926
DOI: 10.1016/j.jaci.2009.01.051

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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