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Article

The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study.

The Journal of allergy and clinical immunology - 1 Apr 2008

Henderson John, Northstone Kate, Lee Simon P, Liao Haihui, Zhao Yiwei, Pembrey Marcus, Mukhopadhyay Somnath, Smith George Davey, Palmer Colin N A, McLean W H Irwin, Irvine Alan D

Abstract excerpt

BACKGROUND: Atopic disease is a major health problem. Mutations in the filaggrin gene (FLG) confer major susceptibility to eczema and related asthma. OBJECTIVE: We sought to determine the natural history and burden of atopic disease conferred by the 2 most common FLG mutations in a large, populat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18325573
DOI: 10.1016/j.jaci.2008.01.026

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18325573-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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