Article
Filaggrin gene mutations in relation to contact allergy and hand eczema in adolescence.
Contact dermatitis - 1 Mar 2020
Lagrelius Maria, Wahlgren Carl-Fredrik, Bradley Maria, Melén Erik, Kull Inger, Bergström Anna, Lidén Carola
Abstract excerpt
BACKGROUND: Filaggrin is an important protein for structure and function of the skin barrier. Filaggrin gene (FLG) mutations are known to result in dry skin, impaired skin barrier, and increased risk for atopic dermatitis. However, it is not clear whether these mutations are associated with contact allergy or hand eczema in adolescence. OBJECTIVES: The purpose of this study was to investigate whether FLG...
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