Article
Filaggrin gene variants and atopic diseases in early childhood assessed longitudinally from birth.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Sept 2010
Bønnelykke Klaus, Pipper Christian B, Tavendale Roger, Palmer Colin N A, Bisgaard Hans
Abstract excerpt
Copenhagen Prospective Study on Asthma in Childhood (COPSAC) was one of the discovery cohorts of the association between eczema and variants in the filaggrin coding gene (FLG). Here, we study the FLG-associated risk of asthma symptoms in early life and describe the temporal relationship in the development of the different FLG-associated atopic outcomes: asthma, sensitization and eczema, assessed longitudinally...
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