Article
Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Mar 2022
Venter Carina, Palumbo Michaela P, Sauder Katherine A, Glueck Deborah H, O'Mahony Liam, Yang Ivana, Davidson Elizabeth J, Brough Helen A, Holloway John W, Fleischer David M, Ben-Abdallah Miriam, Dabelea Dana
Abstract excerpt
BACKGROUND: Filaggrin (FLG) loss-of-function mutations in children and maternal diet in pregnancy have been implicated in child allergy outcomes. This paper studies the questions: "do FLG mutations modify the effect of maternal diet on the odds of development of allergic diseases?" and "which factor leads to the highest rate of diagnosis allergic diseases over time, maternal diet, or FLG mutations?". METHODS:...
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