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Article

Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels.

Genetic epidemiology - 1 Jul 2017

Dennis Jessica, Medina-Rivera Alejandra, Truong Vinh, Antounians Lina, Zwingerman Nora, Carrasco Giovana, Strug Lisa, Wells Phil, Trégouët David-Alexandre, Morange Pierre-Emmanuel, Wilson Michael D, Gagnon France

Abstract excerpt

Tissue factor pathway inhibitor (TFPI) regulates the formation of intravascular blood clots, which manifest clinically as ischemic heart disease, ischemic stroke, and venous thromboembolism (VTE). TFPI plasma levels are heritable, but the genetics underlying TFPI plasma level variability are poorly understood. Herein we report the first genome-wide association scan (GWAS) of TFPI plasma levels, conducted in 251...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28421636
DOI: 10.1002/gepi.22049

Genes

TFPI

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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