Article
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors.
Circulation - 18 Oct 2022
Thibord Florian, Klarin Derek, Brody Jennifer A, Chen Ming-Huei, Levin Michael G, Chasman Daniel I, Goode Ellen L, Hveem Kristian, Teder-Laving Maris, Martinez-Perez Angel, Aïssi Dylan, Daian-Bacq Delphine, Ito Kaoru, Natarajan Pradeep, Lutsey Pamela L, Nadkarni Girish N, de Vries Paul S, Cuellar-Partida Gabriel, Wolford Brooke N, Pattee Jack W, Kooperberg Charles, Braekkan Sigrid K, Li-Gao Ruifang, Saut Noemie, Sept Corriene, Germain Marine, Judy Renae L, Wiggins Kerri L, Ko Darae, O'Donnell Christopher J, Taylor Kent D, Giulianini Franco, De Andrade Mariza, Nøst Therese H, Boland Anne, Empana Jean-Philippe, Koyama Satoshi, Gilliland Thomas, Do Ron, Huffman Jennifer E, Wang Xin, Zhou Wei, Manuel Soria Jose, Carlos Souto Juan, Pankratz Nathan, Haessler Jeffery, Hindberg Kristian, Rosendaal Frits R, Turman Constance, Olaso Robert, Kember Rachel L, Bartz Traci M, Lynch Julie A, Heckbert Susan R, Armasu Sebastian M, Brumpton Ben, Smadja David M, Jouven Xavier, Komuro Issei, Clapham Katharine R, Loos Ruth J F, Willer Cristen J, Sabater-Lleal Maria, Pankow James S, Reiner Alexander P, Morelli Vania M, Ridker Paul M, Vlieg Astrid van Hylckama, Deleuze Jean-François, Kraft Peter, Rader Daniel J, Min Lee Kyung, Psaty Bruce M, Heidi Skogholt Anne, Emmerich Joseph, Suchon Pierre, Rich Stephen S, Vy Ha My T, Tang Weihong, Jackson Rebecca D, Hansen John-Bjarne, Morange Pierre-Emmanuel, Kabrhel Christopher, Trégouët David-Alexandre, Damrauer Scott M, Johnson Andrew D, Smith Nicholas L
Abstract excerpt
BACKGROUND: Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand discovery of new genetic...
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