Article
A locus on chromosome 2 influences levels of tissue factor pathway inhibitor: results from the GAIT study.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2005
Almasy L, Soria J M, Souto J C, Warren D M, Buil A, Borrell M, Muñoz X, Sala N, Lathrop M, Fontcuberta J, Blangero J
Abstract excerpt
OBJECTIVE: Levels of tissue factor pathway inhibitor (TFPI) have been associated with arteriosclerosis and thrombotic disease. Although a genetic component to variation in TFPI levels is well-documented, no systematic genome-wide screens have been conducted to localize genes influencing levels of TFPI. METHODS AND RESULTS: We studied TFPI levels in 397 individuals in 21 Spanish families participating in the...
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