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Article

Genetic determinants of tissue factor pathway inhibitor plasma levels.

Thrombosis and haemostasis - 1 Aug 2015

Dennis J, Kassam I, Morange P-E, Trégouët D-A, Gagnon F

Abstract excerpt

Tissue factor pathway inhibitor (TFPI) impedes early stages of the blood coagulation response, and low TFPI plasma levels increase the risk of thrombosis. TFPI plasma levels are heritable, but specific genetic determinants are unclear. We conducted a comprehensive review of genetic risk factors for TFPI plasma levels and identified 26 studies. We included 16 studies, as well as results from two unpublished...

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Source

Identifiers

PMID: 25879386
DOI: 10.1160/TH14-12-1043

Genes

TFPI
APOE
GLA
JAK2
PROS1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Genetic determinants of tissue factor pathway inhibitor plasma levels.PMID 25879386Read ↗

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