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Article

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.

Thrombosis and haemostasis - 1 Feb 2018

Stanne Tara M, Olsson Maja, Lorentzen Erik, Pedersen Annie, Gummesson Anders, Gils Ann, Jood Katarina, Engström Gunnar, Melander Olle, Declerck Paul J, Jern Christina

Abstract excerpt

Thrombin-activatable fibrinolysis inhibitor (TAFI) plays a central role in haemostasis, and plasma TAFI concentrations are heritable. Candidate gene studies have identified several variants within the gene encoding TAFI, CPB2, that explain part of the estimated heritability. Here, we describe an exploratory genome-wide association study to identify novel variants within and outside of the CPB2 locus that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29378355
DOI: 10.1160/TH17-04-0249
PMCID: PMC6260132

Genes

CPB2
MAF

Provenance

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