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Article

AMPK activation reduces the number of atheromata macrophages in ApoE deficient mice.

Atherosclerosis - 1 Mar 2017

Wang Jing, Ma Ang, Zhao Ming, Zhu Haibo

Abstract excerpt

BACKGROUND AND AIMS: CC chemokine receptor 2 (Ccr2) governs migration of inflammatory Ly6Chi monocytes from the bone marrow (BM) to the circulating blood, which is a key step for macrophage accumulation during progression of atherosclerosis. Hyperlipidemia is often accompanied by low AMP-activated kinase (AMPK) activity and increased expression of Ccr2. The aim of this study was to examine whether there is a link...

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PMID: 28235712
DOI: 10.1016/j.atherosclerosis.2017.01.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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