Article
Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release.
The Journal of cell biology - 2 Jan 2017
Bruckner Joseph J, Zhan Hong, Gratz Scott J, Rao Monica, Ukken Fiona, Zilberg Gregory, O'Connor-Giles Kate M
Abstract excerpt
The strength of synaptic connections varies significantly and is a key determinant of communication within neural circuits. Mechanistic insight into presynaptic factors that establish and modulate neurotransmitter release properties is crucial to understanding synapse strength, circuit function, and neural plasticity. We previously identified Drosophila Piccolo-RIM-related Fife, which regulates neurotransmission...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
